The Carcinogenic Effect of a Papilloma Virus on the Tarred Skin of Rabbits
نویسندگان
چکیده
The Shope papilloma virus elicits carcinomas forthwith, as well as papillomas in great variety, when it is distributed by way of the blood stream to the tarred epidermis of domestic rabbits. The phenomenon will be analyzed in succeeding papers with the aid of additional instances.
منابع مشابه
Comparison of therapeutic effects of intralesional injection of bleomycin and cryotherapy on common warts of hands and feet
Background and aim: Warts are the most common clinical presentation of human papilloma virus infection of human skin and mucosa. They are more common on hand, foot, face and genital area. They are benign skin colour lesions with different clinical forms. There is no specific treatment for them. In this trial the therapeutic effect of intralesional injection of bleomycin and cryotherapy on...
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Areas of rabbit skin previously rendered hyperplastic with turpentine were scarified, inoculated with the Shope papilloma virus, and covered with a dressing that contained 20-methylcholanthrene (MC) or 9:10-dimethyl-1:2-benzanthracene (9:10). The dressing was left on until healing had been well completed, a matter of 5 to 7 days. The papillomas which subsequently arose often appeared later, wer...
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A benign, infectiqus, cutaneous tumor of rabbits, the Shope papilloma, is caused by a virus that upon inoculation in either domestic or cottontail rabbits induces papiUomas with great regularity (1). These tumors are not infrequently followed by cancers (2-6). On attempted recovery of the virus from these two varieties of rabbits, however, a marked difference in host reactivity becomes apparent...
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The carcinomas deriving from the papillomas induced with a virus in domestic rabbits (1) have this virus as their primary cause. The present paper is concerned with the carcinogenic effect of various strains of the virus,--meaning thereby the infective materials procured from the "spontaneous" papillomas of different cottontail rabbits,--and with the influence of the concentration of the inocul...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 68 شماره
صفحات -
تاریخ انتشار 1938